For more than 70 years, Takeda has supplied vaccines to protect the health of people in Japan. Today, Takeda’s global vaccine business is applying innovation to tackle some of the world’s most challenging infectious diseases, such as dengue, COVID-19, pandemic influenza and Zika.

Therapeutic Focus - Vaccines | Takeda Pharmaceuticals

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For more than 70 years, we have supplied routine vaccines to help protect the health of people in Japan including for measles, rubella and mumps. Today, we're expanding our global vaccine business by relying on innovation to tackle some of the world's most challenging infectious diseases, such as dengue, COVID-19 and pandemic influenza.

Our team brings an outstanding track record and a wealth of knowledge in global vaccine development and manufacturing to advance a pipeline of vaccines to help address some of the most pressing public health needs.

Our mission is to develop and deliver innovative vaccines that tackle some of the more challenging problems in public health and help improve the health of people around the world.


### Dengue

* A mosquito-borne disease that continues to spread around the world.4

* Estimated that half of the world's population is at risk of dengue infection.4

### COVID-19

* Caused by a new coronavirus, SARS-CoV-2, first identified in December of 2019.5

* COVID-19 cases have been identified worldwide.6

### Pandemic Influenza

* Influenza viruses are constantly changing, making it possible for them to infect people and easily spread on rare occasions.7

* Last three pandemics killed approximately 1.1 million (1957), 1 million (1968) and 0.2-0.6 million (2009) people.8,9,10

## Disease areas



* Vaccines prevent 3.5 to 5 million deaths each year and have transformed global public health.1

* Vaccines are one of the most cost-effective ways to save lives.2

* 50 million deaths can be prevented through immunization between 2021 and 2030.3

## The value of vaccination



## Educational resources

#### TIDES: Takeda’s Pivotal Phase 3 Dengue Clinical Trial



http://assets-dam.digisourcetech.com/image/upload/v1715710629/Global/Areas%20of%20focus/Vaccines/tides.pdf

world map with endemic countries highlighted in red and connecting lines to non-endemic countries

#### Dengue in Non-Endemic Countries



http://assets-dam.digisourcetech.com/image/upload/v1715965379/Global/Areas%20of%20focus/Vaccines/dengue-in-no-endemic-countries.pdf

#### Behind Vaccine Development: The Clinical Trial Process



http://assets-dam.digisourcetech.com/image/upload/v1715710509/Global/Areas%20of%20focus/Vaccines/behind-vaccine-development.pdf

#### Dengue in Endemic Countries



http://assets-dam.digisourcetech.com/image/upload/v1715965379/Global/Areas%20of%20focus/Vaccines/dengue-in-endemic-countries.pdf

#### Takeda Vaccines



http://assets-dam.digisourcetech.com/image/upload/v1714592073/Global/Areas%20of%20focus/Vaccines/VBU_fact_sheet.pdf

## Resources



### Videos

Learn more about the global burden of dengue on [our video channel](http://youtube.com/playlist?list=PLdEbUoUDW_51Vv9y22KiZK1s0EG1u-RdW\&si=QY6jAOzIEV3o2p5Q).


## Our Stories



The burden of dengue and hope amidst hardship

/our-impact/our-stories/the-burden-of-dengue-and-hope-amidst-hardship/

Beatrice Loesch, operational excellence deployment leader in Global Manufacturing and Supply, giving a speech.

Haunted by dengue, she fights social inequities

/our-impact/our-stories/haunted-by-dengue-she-fights-social-inequities/

Young victims of an outbreak of dengue fever crowd the children's ward of the government-run Quirino Memorial Hospital in Manila

What drives our dengue researchers? Seeing the disease up close


/our-impact/our-stories/what-drives-our-dengue-researchers/

A father's experience with dengue


/our-impact/our-stories/a-father-experience-with-dengue/

## References

1.	World Health Organization. Vaccines and Immunization. Retrieved April 26, 2024.
2.	GAVI. Cost-effective. February 2020. Retrieved April 26, 2024.
3.	CDC. Fast Facts on Global Immunization. April 2023, Retrieved April 26, 2024.
4.	World Health Organization. Dengue and Severe Dengue. World Health Organization. Published April 23, 2024.
5.	World Health Organization. Coronavirus disease (COVID-19) pandemic. Retrieved April 26, 2024.
6.	World Health Organization. WHO Coronavirus (COVID-19) Dashboard. Retrieved April 26, 2024.
7.	Centers for Disease Control and Prevention. Past Pandemics. August 2018. Retrieved April 26, 2024.
8.	Centers for Disease Control and Prevention. 1957-1958 Pandemic (H2N2 virus). January 2019. Retrieved April 26, 2024.
9.	Centers for Disease Control and Prevention. 1968 Pandemic (H3N2 virus). January 2019. Retrieved April 26, 2024.
10.	Centers for Disease Control and Prevention. 2009 H1N1 Pandemic (H1N1pdm09 virus). June 2019. Retrieved April 26, 2024.


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